The store in Cluj-Napoca was opened Thursday and that in Baia Mare Friday.
Profi is present in 36 counties and employs 4,500 people.
The retailer is owned by investment fund Enterprise Investors.
It registered net profit of 13.1 million lei (EUR2.9 million) last year and sales of RON1.15 billion, up from RON934 million in 2011. Profi expects its sales will rise 20% in 2013.